Transcript of Insensibilidad Congenita al Dolor. Comprender las características principales de los receptores, principalmente el tacto. Analizar. Insensibilidad congénita al dolor. Historia Desde su descripción en por Dearborn, los transtornos de percepción de dolor de tipo. Que es?? Insensibilidad congénita al dolor. Es un raro trastorno autosómico recesivo. Causada por una mutación genética que impide la.

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Congenital insensitivity to pain CIPalso known as congennita analgesiais one or more rare conditions in which a person cannot feel and has never felt physical pain. Because feeling physical pain is vital for survival, CIP is an extremely dangerous condition. For people with this disorder, cognition and sensation are otherwise normal; for instance, patients can still feel discriminative touch though not always temperature [3]and there are generally no insensibilldad physical abnormalities.

Because children with the disorder cannot feel pain, they may not respond to problems, thus being at insensibilidac higher risk of more severe diseases. Children with this condition often sustain oral cavity damage both in and around the oral cavity such as having bitten off the tip of their tongue or fractures to bones.

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There are generally two types of non-response exhibited: It may be that the condition is caused by ccongenita production of endorphins in the brain. Patients with such mutations are congenitally insensitive to pain and lack other neuropathies.

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There are three mutations in SCN9A: WX, located in the P-loop of domain 2; IX, located in the S2 segment of domain 2; and SX, located dolr the linker region between domains 1 and 2. This results in a insensibiildad non-functional protein. As these channels are likely involved in the formation and propagation of action potentials in such neurons, it is expected that a loss of function mutation in SCN9A leads to abolished nociceptive pain propagation.

PRDM12 gene is normally switched on during the development of pain-sensing nerve cells. Developmental disabilities such as autism can include varying degrees of pain insensitivity as a sign. The opioid antagonist naloxone allowed a woman with congenital insensitivity to pain to experience it for the first time. Congenital insensitivity to pain is found in Insensibjlidada village in Kiruna Municipality in northern Swedenwhere nearly 40 cases have been reported.

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Insensibilidad Congenita al Dolor by Cristobal Perez-luco on Prezi

Some Americans also have it. From Wikipedia, the free encyclopedia.

Understanding Pain for Better Clinical Practice: Retrieved April 13, The Five Senses and Beyond: The Encyclopedia of Perception. The people who feel no pain”.

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